A platform for collaborations in respiratory research in Sweden
Anchor: intro

Introduction

This page offers an overview of the metadata included into the studies of Breathe Sweden, aimed at enhancing collaboration across research programs. Through combined efforts and pooling of already collected data, research questions can be addressed in a more effective and powerful way.

The database is organized into 12 sections: (1) Socio-demographics, (2) Allergy, (3) Asthma, (4) COPD, (5) COVID-19, (6) Inflammation, (7) Other lab analyses, (8) Genetic data, (9) Lung function, (10) Environmental exposures, (11) Linked registers and (12) Questionnaires.

This setup allows you to explore variables in a specific research program or directly in your area of interest across all studies of Breathe Sweden. If you are interested in collaborating with any programs or want to find out more about the data, please contact the project coordinator of Breathe Sweden (contact information at bottom of this page).

Anchor: Sections

Sections

Anchor: Socio-demographics

Socio-demographics

VariableNo. of cohorts with variable
Body mass index (BMI)12
Body fat percentage7
Health/parental/unemployment insurance8
Smoking history12
+12 more variables (see Excel file below)

Anchor: Allergy

Allergy

VariableNo. of cohorts with variable(s)
Skin prick test (SPT; various allergens)5
Total immunogloublin E (tIgE)7
ImmunoCAP™ Phadiatop7
Specific IgE (sIgE; various allergens, incl. CRD)7
+87 more variables (see Excel file below)

Anchor: Asthma

Asthma

VariableNo. of cohorts with variable
Spirometry (FEV₁, FEV₁/FVC, FVC; pre and post bronchodilator)9
Fractional Exhaled Nitric Oxide (FeNO)7
Bronchial hyper-responsiveness (AHR/BHR) / bronchial provocation test (BPT)5
Asthma Control Test (ACT)7
+24 more variables (see Excel file below)

Anchor: COPD

COPD

VariableNo. of cohorts with variable
Spirometry (FEV₁, FEV₁/FVC, FVC; pre and post bronchodilator)9
COPD Assessment Test (CAT)3
Diffusing capacity (DLCO)2
Smoking history12
+18 more variables (see Excel file below)

Anchor: COVID-19

COVID-19

COVID-19 data is included in 8 of our cohorts. The collected variables in the different studies vary, ranging from the date of positive PCR testing in the acute phase to variables related to post-COVID-19 effects and vaccination status.


Anchor: Inflammation

Inflammation

Variables reflecting inflammation are collected in 7 cohorts and include exhaled nitric oxide (FENO) as a measure of Th2 airway inflammation, blood eosinophil count, and IL-6 in the blood.


Anchor: Other lab analyses

Other lab analyses

In this section, variables covering analysis of both blood, urine, saliva and feaces are collected. In total, 28 variables are included.


Anchor: Genetic data

Genetic data

Different variables related to genetic data are found in 7 cohorts, including GWAS and EWAS.


Anchor: Lung function

Lung function

VariableNo. of cohorts with variable
Spirometry (FEV₁, FEV₁/FVC, FVC; pre and post bronchodilator)9
Oscillometry4
Slow vital capacity (SVC; pre and post bronchodilator)3
Diffusing capacity (DLCO)2
+28 more variables (see Excel file below)

Anchor: Environmental exposures

Environmental exposures

Variables reflecting both indoor and outdoor exposures are included in this section. As an example, variables related to outdoor air pollution are collected in 3 cohorts.


Anchor: Linked registers

Linked registers

VariableNo. of cohorts with variable
National Medical Birth Register (prenatal/pregnancy, delivery, and neonatal care data)6
National Patient Register (specialist inpatient and outpatient care)8
National Cause of Death Register8
National Prescribed Drug Register7
Health/parental/unemployment insurance (LISA; nationwide)8
+28 more variables (see Excel file below)

Anchor: Questionnaires

Questionnaires

VariableNo. of cohorts with variable
Asthma Control Test (ACT)7
Modified Medical Research Council (mMRC) dyspnea scale6
COPD Assessment Test (CAT)3
EQ-5D (health-related quality of life)3
+15 more variables (see Excel file below)

Anchor: full-list-of-metadata

Full list of metadata

Below you may find the complete list of metadata across all cohorts of Breathe Sweden

Anchor: contacts

Contact information

Bright Nwaru
Project Leader
bright.nwaru@gu.se

Sanna Kjellberg
Project Coordinator
sanna.kjellberg@gu.se